Publications

Selected Publications

For all publications, visit Experts@Minnesota

2024

Wang H*, Herman A, Barrow F, Fredrickson G, Parthiban P, and Revelo XS. Single-Cell RNA Sequencing Reveals a Reprogramming of Hepatic Immune Cells and a Protective Role for B cells in MASH-Driven Hepatocellular Carcinoma. Hepatology Communications 2024 [Accepted].

Parthasarathy G, Venkatesan N, Sidhu GS, Song MJ, Liao CY, Barrow F, Mauer A, Sehrawat T, Nakao Y, Daniel PV, Dasgupta D, Pavelko K, Revelo XS, and Harmeet Malhi. Deletion of Sphingosine 1-Phosphate Receptor 1 in Myeloid Cells Reduces Hepatic Inflammatory Macrophages and Attenuates MASH. Hepatology Communications 2024 [In press].

Fredrickson G*, Florczak K, Barrow F, Dietsche K, Parthiban P, Almutlaq R, Abujamra M, Demirchian M, Kieu T, Wang H, Adeyi O, Staley C, Nguyen H, Jahansouz C, Ikramuddin S, and Revelo XS. Hepatic lipid-associated macrophages mediate the beneficial effects of bariatric surgery against NASH. Hepatology 2024 doi: 10.1097/HEP.0000000000001098.

Cordeiro B, Ahn JJ, Gawde S, Ucciferri C, Alvarez-Sanchez N, Revelo XS, Stickle N, Massey K, Brooks DG, Guthridge JM, Pardo G, Winer DA, Axtell RC, and Dunn SE. Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females. Cell Metabolism 2024; 36(10):2298.

Patterson MT, Xu Y, Hillman H, Osinski V, Schrank PR, Kennedy AE, Barrow F, Zhu A, Tollison S, Shekhar S, Stromnes IM, Tassi I, Wu D, Revelo XS, Binstadt BA, Williams JW. Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability. ATVB 2024; 44(7):1646.

2023

Patterson MT, Firulyova MM, Xu Y, Hillman H, Bishop C, Zhu A, Hickok G, Schrank P, Ronayne C, Caillot Z, Fredrickson G, Kennedy A, Neels, J, Chinetti G, Revelo XS, Stromnes I, Ivanov S, Bold T, Zaitsev K, and Williams J. Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis. Nature Cardiovascular Research 2023; 2(11):1015.

Vetter TA, Parthiban P, Stevens JA, Revelo XS, Kohr MJ, Townsend D. Reduced cardiac antioxidant defenses mediate increased susceptibility to workload-induced myocardial injury in males with genetic cardiomyopathy. J Mol Cell Cardiol 2024;190:24-34.

Barrow F*, Fredrickson G, Wang H, and Revelo XS. Functional phenotyping of hepatic lymphocytes in murine MASH by mass cytometry. Star Protocols 2023;4(4):102743.

Souza-Neto F, Revelo XS, and van Berlo JH. Macrophages Remember When Your Heart Was Broken. JACC: Basic to Translational Science 2023 8(7):798-800

Liao C, Barrow F, Nakao Y., Mauer A., Fredrickson G, Song M., Sehrawat T., Dasgupta D., Rondell D., Revelo XS, and Malhi H. Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis. Frontiers in Immunology 2023 14:1130184.

2022

SenNet Consortium (Revelo XS as part of the University of Minnesota TMC). NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health. Nature Aging 2022; 2:1090.

Liu H, Huang Y, Zhao Y, Feng F, Kang G, Wang X, Liu M, Shi G, Revelo XS, Bernlohr D, and Dudley S. Inflammatory Macrophage Interleukin-1β Mediates High Fat Diet-Induced Heart Failure with Preserved Ejection Fraction. JACC: Basic to Translational Science 2022 28(28):3595.

Hirsova P and Revelo XS. Editorial: Immune Mechanisms of Inflammation in NASH. Frontiers in Endocrinology 2022 13:1039238. doi: 10.3389/fendo.2022.1039238.

Mattos AZ, Debes JD, Vogel A, Arrese M, Revelo XS, Pase THS, Manica M, and Mattos AA. Nonalcoholic fatty liver disease-related hepatocellular carcinoma: is there a role for immunotherapy? (Invited Review). World Journal of Gastroenterology 2022 28:3595. 

Zhao M, Ren K, Xiong X, Xin Y, Kim A, Maynard J, Zou Y, Battist A, Koneripalli N, Huang Z, Zhang Z, Yu J, Wang H*, Salgado O, Hogquist KA, Revelo XS, Burlingame AL, Gao X, Lin Z; von Moltke J, and Ruan HB. Epithelial STAT6 O-GlcNAcylation drives anti-helminth immunity via a concerted alarmin response. Immunity 2022 55(4):623.

Barrow F* and Revelo XS. The B side of B cells in NAFLD (Invited Editorial). Hepatology 2022 doi: 10.1002/hep.32481.

2021

Hirsova P, Badimele W, Wang H*, Povero D, and Revelo XS. Emerging Roles of T cells in the Pathogenesis of NASH and Hepatocellular Carcinoma. Frontiers in Endocrinology 2021. 12:760860. 

Revelo XS, Parthiban P*, Barrow F*, Fredrickson G*, Wang H*, Yücel D, Chen C, and van Berlo J H. Cardiac macrophages prevent fibrosis and stimulate angiogenesis in compensated hypertrophy. Circulation Research 2021 129:1086. Featured in the cover and selected for the editorial “Resident macrophages in the heart: cardioprotective under pressure” Circulation Research 2021. 129:1102.

Lopresti MW, Cui W, Abernathy B, Fredrickson G*, Barrow F*, Desai AS, Revelo XS, and Mashek DG. Hepatic Lysosomal Acid Lipase Overexpression Worsens Hepatic Inflammation in Mice Fed a Western Diet. Journal of Lipid Research 2021 5:100133.

Fredrickson G*, Barrow F*, Dietsche K*, Parthiban P*, Khan S, Robert S*, Demirchian M*, Wang H*, and Revelo XS. Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH. Molecular Metabolism 2021 53:101270. 

Barrow F*, Khan S, Wang H*, and Revelo XS. The Emerging Role of B Cells in the Pathogenesis of NAFLD. Hepatology 2021 74(4):2277.

Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, Dotan I, Revelo XS, Shi SY, Le H, Schroer S, Dodington D, Park D, Kim D, Febbraro D, Ruel I, Genest J, Kim R, Mak T, Winer DA, Robbins C, and Woo M. DJ1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophage. Scientific Reports 2021 11(1):4723.

Barrow F*, Khan S, Fredrickson G*, Wang H*, Dietsche K*, Parthiban P*, Robert S*, Kaiser T, Winer S, Herman A, Adeyi O, Mouzaki M, Khoruts A, Staley C, Hogquist KA, Winer DA, and Revelo XS. Microbiota-Driven Activation of Intrahepatic B Cells Aggravates Nonalcoholic Steatohepatitis through Innate and Adaptive Signaling#. Hepatology 2021 74(2):704. Featured in the issue cover.

Chakraborty M, Chu K, Shrestha A, Revelo XS, Zhang X, Gold MJ, Khan S, Lee M, Huang C, Akbari M, Barrow F*, Chan YT, Kotoulas NK, Jovel J, Pastrello C, Kotlyar C, Goh C, Michelakis E, Clemente-Casares X, Ohashi PS, Engleman EG, Winer S, Jurisica I, Tsai S, and Winer DA. Mechanical Stiffness Controls Dendritic Cell Metabolism and Function. Cell Reports 2021 34(2):108609. 

2020

Khan S, Chan YT, Revelo XS, and Winer DA The Immune Landscape of Visceral Adipose Tissue During Obesity and Aging. Frontiers in Endocrinology 2020 11:267.

Parthasarathy G., Revelo XS, and Malhi H. Pathogenesis of Nonalcoholic Steatohepatitis: An Overview. Hepatology Communications 2020 4(4):478.